| 名稱(chēng) | Recombinant Human BMP-4 |
| 型號(hào) | |
| 更新時(shí)間 | 2023-09-24 |
| 特點(diǎn) | 骨形成蛋白(bmp)構(gòu)成一個(gè)亞科內(nèi)TGF-β總科的結(jié)構(gòu)相關(guān)信號(hào)蛋白。這個(gè)總科的成員廣泛分布于整個(gè)身體,并參與各種生理過(guò)程在兩個(gè)前和產(chǎn)后的生活。像BMP-7 BMP-4參與骨骼和軟骨的開(kāi)發(fā)和維護(hù)。BMP-4表達(dá)降低與許多骨相關(guān)疾病。} |
產(chǎn)品展示 / PRODUCTS
- 詳細(xì)內(nèi)容
一.產(chǎn)品名稱(chēng)：Recombinant Human BMP-4
二.貨號(hào)Catalog Number:AF-120-05ET
三.同義Synonyms:BMP-2B, DVR4
四.描述Description:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa. Manufactured using all non-animal reagents.
五.AA序列AA Sequence:
KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
六.來(lái)源Source:E.coli
Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
七.生物活性Biological Activity:
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
八.交叉性Cross Reactivity:Mouse, Human, Rat
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電話/傳真：13366128764
手機(jī)：15311648455
地址：北京市海淀區(qū)廂黃旗2號(hào)樓1層4-179室